| Console: | Nintendo Game Boy |
| TV Standard: | PAL |
| Country: | United Kingdom of Great Britain and Northern Ireland |
| Developer(s): | Nintendo R&D1 |
| Publisher(s): | Nintendo |
| Release Date: | 1991-04-30 |
| Players: | 2 |
| Co-op: | No |
| ESRB: | E - Everyone |
| Type: | Puzzle |
It's Dr. Mario for an intense new challenge! Mario throws multi-shaded vitamin capsules into a bottle that contains an ugly variety of nasty viruses. You can move, shift or spin the capsules as they fall. Arrange them to align with other capsules on top of a virus. If you can get 4 or more of the same shade in a row, POOF! They disappear! Destroy all of the viruses in the bottle and you progress to the next round where things get even more difficult. Dr. Mario, with germs that are fun to catch.
Game Player of Dr. Mario on Nintendo Game BoyGenerally, you can review the controls (keyboard) setting during each game in the screen before it starts. Use the arrow keys and “Z”, “X”, “A”, “S”, “Q”, “E” buttons to play, or customize yourself with your gamepad or keyboard.
| Keyboard | Controls |
| ← → ↑ ↓ | Directions for LEFT, RIGHT, UP, DOWN |
| Enter ↵ | START |
| Shift | SELECT |
| Z | A |
| X | B |
| A | X |
| S | Y |
| Q | L |
| E | R |
